Status:

COMPLETED

Vancomycin and Daptomycin Plus Cefazolin for Preoperative Vascular Surgery Prophylaxis

Lead Sponsor:

CAMC Health System

Conditions:

MRSA Infections

Eligibility:

All Genders

18-90 years

Brief Summary

This study prospectively selects the patients to examine the effectiveness of the investigators' current standard of prophylaxis prior to vascular surgery and to compare the effectiveness of vancomyci...

Detailed Description

According to Medqic.org (site for the Surgical Care Improvement Project) the current recommended drug of choice for prophylaxis prior to vascular surgery is Cefazolin (Ancef). The exception would be t...

Eligibility Criteria

Inclusion

  • Patients greater than 18 years of age undergoing vascular surgery including carotid procedures and a vascular access procedure (Fistula or Graft).

Exclusion

  • Patients with an allergy to daptomycin or vancomycin.
  • Patients with chronic wounds.
  • Prior colonization of MRSA.
  • Increased MRSA rate facility wide.
  • Continuous inpatient stay \>27 hrs prior to surgical procedure.
  • Patients with active infection requiring antibiotics preoperatively.
  • Patients with a history of MRSA colonization or infection, HIV, admission for \>3 months in an acute care center or long-term care center, penicillin allergy or penicillin allergy and on dialysis.
  • Dialysis patients.

Key Trial Info

Start Date :

August 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2010

Estimated Enrollment :

169 Patients enrolled

Trial Details

Trial ID

NCT00967941

Start Date

August 1 2007

End Date

August 1 2010

Last Update

February 28 2020

Active Locations (1)

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Vascular Center of Excellence

Charleston, West Virginia, United States, 25304