Status:
COMPLETED
Interleukin (IL)-13 as a Marker in Pediatrics Asthma
Lead Sponsor:
Rush University Medical Center
Conditions:
Asthma
Eligibility:
All Genders
8-15 years
Brief Summary
Asthma is a very common childhood chronic illness and is generally more severe in African Americans. The investigators attempted to determine whether a specific immune marker is associated with lung f...
Detailed Description
This study examined the relationship between Interleukin (IL)-13 from phytohemagglutinin-activated polymorphonuclear blood cells and asthma severity, lung function (measured as FEV1%), and total serum...
Eligibility Criteria
Inclusion
- African-American race, born in the U.S.
- Age 8-15 years
- Clinical diagnosis of asthma
- Subject is able to understand and follow verbal instructions in English
Exclusion
- Asthma exacerbation in the 4 weeks preceding the research visit
- Oral/IV steroid use in the 4 weeks preceding the research visit
- Upper or lower respiratory tract infection in the 4 weeks preceding the research visit
- Antibiotic use in the 4 weeks preceding the research visit
- Use of a short-acting bronchodilator during the 6 hours prior to spirometry (lung function testing)
- Use of a long-acting bronchodilator during the 12 hours prior to spirometry (lung function testing)
Key Trial Info
Start Date :
November 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2009
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT00968305
Start Date
November 1 2008
End Date
August 1 2009
Last Update
August 28 2009
Active Locations (1)
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1
Rush University Medical Center; Clinic: University Consultants in Allergy and Immunology
Chicago, Illinois, United States, 60612