Status:
WITHDRAWN
Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain Birthmarks
Lead Sponsor:
University of California, Irvine
Collaborating Sponsors:
Beckman Laser Institute University of California Irvine
Conditions:
Port Wine Stain
Eligibility:
All Genders
16+ years
Phase:
PHASE1
PHASE2
Brief Summary
The researcher want to improve port wine stain (PWS) therapeutic outcome in response to laser therapy. The researcher want to determine whether the combined use of pulsed dye laser (PDL) therapy and t...
Detailed Description
Both topical agents inhibit nuclear factor of activated T-cells (NFAT) which blocks the calcineurin/NFAT pathway inhibiting endothelial cell proliferation and angiogenesis, which could be very useful ...
Eligibility Criteria
Inclusion
- 16 years of age and older
- Have PWS suitable for comparison testing as determined by the study doctor
Exclusion
- Less than 16 years old
- Are pregnant
- Have skin cancer
- Currently taking immunosuppressive or steroids or photosensitizing drugs
- Current participation in any other investigational drug evaluation
- Concurrent use of known photosensitizing drugs
Key Trial Info
Start Date :
November 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00969397
Start Date
November 1 2009
End Date
September 1 2011
Last Update
November 1 2022
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