Status:
COMPLETED
Cardiac Function and Morphology Evaluated by Magnetic Resonance Imaging in Growth Hormone Deficiency and Acromegaly
Lead Sponsor:
Herlev Hospital
Conditions:
Growth Hormone Deficiency
Cardiac Function
Eligibility:
All Genders
18-70 years
Brief Summary
To test the hypothesis that both lack and excess of growth hormone (GH) is associated with cardiac abnormalities. Cardiac function and morphology will be evaluated by MRI before and after treatment.
Detailed Description
It is an open prospective noninterventional clinical study. Treatment and follow-up will be according to usual guidelines, and will be unaffected by inclusion in the study. GHD patients will be treate...
Eligibility Criteria
Inclusion
- Peak GH below 6.0 ng/mL during Pyridostigmine-GHRH test.
- Nadir GH above 0.4 ng/mL and elevated levels of IGF-I during oral glucose tolerance test
Exclusion
- Contraindications for magnetic resonance scan
Key Trial Info
Start Date :
January 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00970463
Start Date
January 1 2006
End Date
May 1 2009
Last Update
September 2 2009
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