Status:
UNKNOWN
Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia
Lead Sponsor:
Bronx VA Medical Center
Conditions:
Hypercholesterolemia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Recently, research studies have shown that patients who have had trouble taking statins every day, are able to take statins if they take them only once or twice a week. The investigators are doing a r...
Eligibility Criteria
Inclusion
- Patients with a history of intolerance to statins
- Patients currently receiving ezetimibe
- Patients willing and able to provide signed informed consent
Exclusion
- Patients receiving a statin (Lipitor, Crestor, Lescol, Simvastatin, or Pravachol)
- Stroke, TIA, myocardial infarction, unstable angina, percutaneous coronary intervention, coronary artery bypass surgery, or major surgery within 3 months
- Cancer undergoing active treatment
- Creatinine clearance \< 40 ml/minute
- Active liver disease or persistent elevation of SGOT or SGPT \> 2 times the upper limit of normal level
- Participation in any clinical study within the last 30 days
- Drug addition or alcohol abuse within the past 6 months
- Use of cyclosporine within the last 3 months
- Use of gemfibrozil within the last month
- Patients unwilling or unable to provide informed consent
- Patients with poor compliance
- Women of childbearing potential
- History of rhabdomyolysis due to statins
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2011
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00972829
Start Date
September 1 2009
End Date
March 1 2011
Last Update
September 10 2009
Active Locations (1)
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1
Bronx VA Medical Center
The Bronx, New York, United States, 10468