Status:

COMPLETED

An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease

Lead Sponsor:

University of Southampton

Collaborating Sponsors:

GlaxoSmithKline

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

35-80 years

Phase:

PHASE4

Brief Summary

This study is investigating the possible mechanisms of action of an inhaled treatment (Seretide), currently used worldwide in millions of patients with COPD (Chronic Obstructive Pulmonary Disease) and...

Detailed Description

We aim to recruit equal numbers of healthy smokers, mild, moderate and severe COPD patients (12 patients to be recruited from each group). These patients will never have been prescribed the components...

Eligibility Criteria

Inclusion

  • \>35yrs.
  • \>10 Pack Years COPD as defined as an FEV1\<70% and an FEV1/FVC ratio of \<70%

Exclusion

  • Asthma
  • Lung cancer
  • Bronchiectasis

Key Trial Info

Start Date :

February 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2012

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT00974805

Start Date

February 1 2010

End Date

February 1 2012

Last Update

December 8 2014

Active Locations (1)

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1

Southampton General Hospital

Southampton, Hampshire, United Kingdom, SO16 6YD