Status:
COMPLETED
Folate Gene Polymorphisms and Cellular Folate Speciation Pilot Study
Lead Sponsor:
Quadram Institute Bioscience
Conditions:
Single Nucleotide Polymorphism
Eligibility:
All Genders
18-65 years
Brief Summary
This pilot study is designed to investigate differences in folate-related genes (single nucleotide polymorphisms) and their relationship to the species of folate present on red blood cells.
Detailed Description
The main questions to be addressed in this pilot study are: 1. what is the type of folate in red blood cells in individuals with different methylterahydrofolate reductase (MTHFR) genotypes 2. what is...
Eligibility Criteria
Inclusion
- Aged 18-65
- Males and females
- Body Mass Index greater than 19.5 and less than 40
- Smokers and non-smokers
Exclusion
- Pregnancy or been pregnant in last 12 months
- Diabetes
- Parallel participation in another research project if total amount of blood from combined studies is greater than 470ml
- Participation in another research project where blood samples were taken within the past 4 months, unless total blood volume does not exceed 470ml
- Any person related to or living with a member of the study team
- Has donated or intends to donate blood within 16 weeks (prior to or after) the study
Key Trial Info
Start Date :
February 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00975364
Start Date
February 1 2009
End Date
December 1 2010
Last Update
February 18 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Institute of Food Research
Norwich, Norfolk, United Kingdom, NR4 6JF