Status:
COMPLETED
The Arthritis, Diet, and Activity Promotion Trial
Lead Sponsor:
Wake Forest University Health Sciences
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The primary purpose of this study was to determine the effect of dietary weight-loss, exercise training, or a combination of both on physical function in overweight and obese adults with knee osteoart...
Eligibility Criteria
Inclusion
- Age ≥ 60 years.
- BMI ≥ 28 kg/m2.
- Knee pain on most days of the month.
- Sedentary lifestyle pattern (\<20 min exercise per week for last 6 months)
- Self-reported difficulty with at least one of the following: walking 1/4 mile, climbing stairs, kneeling, bending, stooping, shopping, lifting, self-care.
- Radiographic evidence of grade 1-3 knee osteoarthritis.
Exclusion
- Serious medical condition that precludes safe participation in exercise such as heart disease (angina, congestive heart failure), severe hypertension, COPD, renal or liver disease, insulin-dependent diabetes.
- Mini-mental state exam score \<24.
- Inability to walks without a cane.
- Reported alcohol consumption \>14 drinks/week.
- Inability to complete protocol.
- ST segment depression.
- Participation in another research study.
Key Trial Info
Start Date :
November 1 1997
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2000
Estimated Enrollment :
318 Patients enrolled
Trial Details
Trial ID
NCT00979043
Start Date
November 1 1997
End Date
December 1 2000
Last Update
April 14 2023
Active Locations (1)
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1
Wake Forest University
Winston-Salem, North Carolina, United States, 27157