Status:
COMPLETED
A Study of the Pharmacokinetics of Two Formulations of MK-1006 (MK-1006-010 AM1)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
This study will assess the pharmacokinetics of two formulations of MK-1006. The primary hypothesis of this study is that the MK-1006 area under the curve (0 to infinity) and maximum concentration afte...
Eligibility Criteria
Inclusion
- is a male or a female of non-child bearing potential
- has type 2 diabetes (T2D) and is either being treated with diet and exercise alone or with a single or combination oral anti-hyperglycemic agent(s)
- has been a nonsmoker for at least 6 months
Exclusion
- has a history of stroke, chronic seizures, or major neurological disorder
- has a history of major endocrine (except T2D), gastrointestinal, cardiovascular, blood, liver, immune, kidney, respiratory, or genitourinary abnormalities or diseases
- has a history of cancer, except certain skin or cervical cancers or cancer that was successfully treated more than 10 years prior to screening
- has unstable or rapidly progressing diabetic retinopathy and/or neuropathy
- has had an eye infection or other inflammation of the eye in the 2 weeks prior to screening
- has glaucoma or is blind
- has had incisional eye surgery in the last 6 months or laser eye surgery in the last 3 months (Lasik is permitted)
- has a history of type 1 diabetes
- has symptomatic coronary artery disease
- consumes excessive amounts of alcohol and/or caffeine
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00979459
Start Date
September 1 2009
End Date
December 1 2009
Last Update
February 5 2016
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.