Status:

COMPLETED

AZD8683 Single Ascending Dose Study

Lead Sponsor:

AstraZeneca

Conditions:

Healthy Volunteers

Eligibility:

MALE

18-45 years

Phase:

PHASE1

Brief Summary

The aim of the study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8683 following single ascending dose administrations in healthy male subjects.

Eligibility Criteria

Inclusion

  • Provision of signed, written and dated informed consent prior to any study specific procedures
  • Have a body mass index (BMI) between 19 and 30 kg/m2 and weigh at least 50 kg and no more than 100 kg
  • Be non-smoker or ex-smoker who has stopped smoking (or using other nicotine products) for \>6 months prior to study start

Exclusion

  • Any clinically significant disease or disorder
  • Any clinically significant abnormalities at screening examinations
  • Use any prescribed or non-prescribed medication

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00979849

Start Date

October 1 2009

End Date

January 1 2010

Last Update

March 2 2010

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Research Site

Philadelphia, Pennsylvania, United States