Status:
COMPLETED
Colorectal Cancer Screening for Cancer Survivors
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Princess Margaret Hospital, Canada
Conditions:
Colorectal Cancer
Eligibility:
All Genders
35-49 years
Brief Summary
The risk of colorectal cancer (CRC) is significant among cancer survivors treated with abdominal radiation therapy (RT). Further, CRC is once of the few cancers for which there is effective screening....
Detailed Description
Cancer survivors meeting the COG criteria for CRC screening will undergo colonoscopy and removal of colorectal polyps. Documentation of polyp number, location and pathologic characteristics will be ma...
Eligibility Criteria
Inclusion
- Asymptomatic survivors treated with ≥ 25Gy to the abdomen, pelvis or spine, or ≥ 12Gy total body radiation therapy, or ≥ 12Gy whole abdominal RT.
- Patients who have passed ≥10 years following RT
- Patients whose current age is 35-49.
Exclusion
- Patients with signs/symptoms suggestive of CRC or other high-risk features such as:
- Persistent constipation for \>2 weeks in the last month
- One or more unexplained episodes of red blood in the stool in the last month
- One or more unexplained episodes of black stool in the last month
- Unexplained pelvic pain in the last month
- Patients with a history of Crohn's disease or ulcerative colitis
- Patients already taking part in a colorectal screening program defined as any colorectal screening (colonoscopy, sigmoidoscopy, fecal occult blood test) within last 5 years.
- Patients with self-reported history of colorectal polyps.
Key Trial Info
Start Date :
May 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 24 2018
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT00982059
Start Date
May 1 2008
End Date
January 24 2018
Last Update
January 31 2018
Active Locations (2)
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1
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115
2
University Health Network
Toronto, Ontario, Canada, M5G 2M9