Status:

COMPLETED

The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous Nephropathy

Lead Sponsor:

Istanbul University

Conditions:

Nephrotic Syndrome

Glomerulonephritis

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Membranous nephropathy (MN) may also be secondary to many other diseases (e.g., infections, drugs, neoplasms and autoimmune diseases). In this study, the presence of Helicobacter Pylori (H. pylori) an...

Detailed Description

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. It is thought to be mainly a primary or idiopathic form; however, it may also be secondary to many other diseases (e.g., ...

Eligibility Criteria

Inclusion

  • Age between 18-70 years
  • Nondiabetic patients
  • Patients with primary glomerulonephritis
  • Clinical diagnosis of membranous nephropathy, IgA nephropathy or focal segmental glomerulosclerosis confirmed by biopsy
  • Glomerular filtration rate \> 30 mL/min
  • Patients who did not receive Helicobacter pylori eradication therapy within the last three months before enrollment in study

Exclusion

  • Patients with secondary glomerulonephritis
  • Glomerular filtration rate \< 30 mL/min
  • Patients who received Helicobacter pylori eradication therapy within the last three months before enrollment in study
  • Patients with a history of gastric surgery
  • Patients without an informed consent

Key Trial Info

Start Date :

March 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT00983034

Start Date

March 1 2006

End Date

July 1 2009

Last Update

September 23 2009

Active Locations (1)

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Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University

Istanbul, Turkey (Türkiye), 34390