Status:

COMPLETED

Stereotactic Radiation Therapy in Treating Patients With Brain Metastases

Lead Sponsor:

Ohio State University Comprehensive Cancer Center

Conditions:

Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

RATIONALE: Stereotactic radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase II trial is study how well stereotactic radiatio...

Detailed Description

OBJECTIVES: Primary * To determine the neurological death rate following the initiation of conformal stereotactic radiotherapy in patients with 1-3 brain metastases. Secondary * To determine the o...

Eligibility Criteria

Inclusion

  • Histology-confirmed cancer with 1 to 3 symptomatic brain metastases imaged by MRI/CT scans.
  • Have cancer not originating in central nervous system (CNS)
  • Karnofsky score of at least 60
  • Given written consent
  • At least 18 years of age

Exclusion

  • Prior whole brain radiotherapy or prior focal radiotherapy of the metastasis/es considered for this trial.
  • Certain radiosensitive primary tumors such as small cell lung cancer, germ cell tumors, lymphoma, leukemia or multiple myeloma.

Key Trial Info

Start Date :

April 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00983359

Start Date

April 1 2007

End Date

August 1 2012

Last Update

June 6 2017

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States, 43210-1240