Status:

COMPLETED

Clinical Evaluation of Therapy™ Cool Path™ Duo Cardiac Ablation System for the Treatment of Typical Atrial Flutter (AFL)

Lead Sponsor:

Abbott Medical Devices

Conditions:

Typical Atrial Flutter

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to demonstrate that ablation with the Therapy™ Cool Path™ Duo cardiac ablation system can eliminate typical atrial flutter and that its use does not result in an unaccepta...

Detailed Description

This is a prospective, multi-center, non-randomized study (historical data as control) for the evaluating the safety and efficacy of Therapy TM Cool PathTM Duo Ablation System for the treatment of ty...

Eligibility Criteria

Inclusion

  • A signed written Informed Consent
  • Presence of typical atrial flutter (cavotricuspid isthmus dependent)
  • If subjects are receiving antiarrhythmic drug therapy (Class I or Class III AAD)for an arrhythmia other than typical atrial flutter, then the subject needs to be controlled on their medication for at least 3 months. If the subject had typical atrial flutter before starting the AAD(s) (Class I or Class III) and then subsequently had another arrhythmia (i.e. atrial fibrillation), then the 3 month AAD criteria will not apply.
  • One documented occurrence of the study arrhythmia documented by ECG, Holter, telemetry strip, or transtelephonic monitor within the past 6 months
  • In good physical health
  • 18 years of age or older
  • Agree to comply with follow-up visits and evaluation

Exclusion

  • Prior typical atrial flutter ablation treatment
  • Pregnancy
  • Atypical flutter or scar flutter(non-isthmus dependent)
  • Significant coronary heart disease or heart failure; that is unstable angina pectoris and/or uncontrolled congestive heart failure (NYHA Class III or IV) at the time of enrollment
  • A recent myocardial infarction within 3 months of the intended procedure date
  • Permanent coronary sinus pacing lead
  • Tricuspid valvular disease requiring surgery and/or a prosthetic tricuspid heart valve (i.e. significant)
  • Evidence of intracardiac thrombus or a history of clotting disorders
  • Participation in another investigational study
  • Cardiac surgery within 1 month of the intended procedure date
  • Allergy or contraindication to Heparin

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2012

Estimated Enrollment :

188 Patients enrolled

Trial Details

Trial ID

NCT00984204

Start Date

October 1 2009

End Date

January 1 2012

Last Update

February 19 2019

Active Locations (22)

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Page 1 of 6 (22 locations)

1

Regional Cardiology Associates

Sacramento, California, United States, 95819

2

Kansas University Medical Center

Kansas City, Kansas, United States, 66160

3

Central Baptist Hospital

Lexington, Kentucky, United States, 40503

4

Ochsner Medical Center

New Orleans, Louisiana, United States, 70121