Status:

COMPLETED

Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis

Lead Sponsor:

University of Oulu

Conditions:

Glucose Tolerance

Eligibility:

All Genders

18-40 years

Phase:

PHASE4

Brief Summary

This clinical trial is designed to study the effects of rifampicin on the glucose, lipid and hormone homeostasis in healthy volunteers. The main hypothesis is that rifampicin lowers fasting glucose an...

Eligibility Criteria

Inclusion

  • Healthy volunteer
  • Age 18-40 years

Exclusion

  • Any continuous medication
  • Any significant disease
  • Allergy to rifampicin
  • Pregnancy and breast feeding
  • Fear of needles and previous difficult blood samplings
  • Substance abuse
  • Participation in another clinical drug trial within 1 month of enrollment
  • Use of soft contact lenses

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2010

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00985270

Start Date

September 1 2009

End Date

October 1 2010

Last Update

February 10 2011

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Oulu University Hospital

Oulu, Finland, 90220