Status:
COMPLETED
Selective Retina Therapy (SRT) in Patients With Idiopathic Central Serous Retinopathy
Lead Sponsor:
University of Kiel
Collaborating Sponsors:
Medical Laser Center Lübeck, Lübeck, Germany
Institute for Medical Informaties and Statistics Kiel, Germany
Conditions:
Central Serous Chorioretinopathy
Selective Retina Therapy
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
The purpose of this study is to evaluate the efficacy of Selective Retina Therapy (SRT) for treating acute idiopathic central serous chorioretinopathy (ICSC). Patients with acute symptomatic ICSC of a...
Detailed Description
Idiopathic central serous chorioretinopathy (ICSC) is characterized by a serous detachment of the neurosensory retina in the macular region secondary to a focal or retinal pigment epithelial defect. P...
Eligibility Criteria
Inclusion
- Anamnestic reduction of visual acuity
- Atients with best-corrected visual acuity (BCVA) of 20/200 or better
- Presence of subretinal fluid (SRF) on optical coherence tomography (OCT)
- Presence of active angiographic (multi)focal leakage in fluorescein angiography (FA) caused by ICSC but not choroidal neovascularisation (CNV) or other diseases
- Absence of other retinal or ocular diseases (e. g. glaucoma, vessel diseases, vein occlusion or proliferative retinopathy)
- Absence of cataract or media opacities of a degree which precludes taking retinal photographs and FA's
- Absence of angle closure glaucoma which precludes pharmacological dilatation of the pupil.
Exclusion
- Patients who received any previous treatment, including PDT or focal cw laser photocoagulation for ICSC, or who had evidence of CNV, PCV, or other maculopathy on clinical examination or FA were excluded.
- Patients receiving exogenous corticosteroid treatment, with systemic diseases such as Cushing's disease or renal diseases, and pregnant patients also were excluded.
- Informed consent was obtained from all subjects, and the study protocol was approved by the ethics committee of the University of Kiel.
Key Trial Info
Start Date :
April 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2009
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00987077
Start Date
April 1 2007
End Date
January 1 2009
Last Update
September 30 2009
Active Locations (1)
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1
Department of Ophthalmology
Kiel, Schleswig-Holstein, Germany, 24105