Status:
UNKNOWN
The Effect of Selective Serotonin Reuptake Inhibitor (SSRI) Treatment on Affective Symptoms and Fertility Treatment Outcome in Women Undergoing in Vitro Fertilization (IVF)
Lead Sponsor:
Tel-Aviv Sourasky Medical Center
Conditions:
Depression
Anxiety
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Women undergoing IVF show a high prevalence of depressive and anxiety symptoms. Furthermore, stress has harmful consequences on IVF and pregnancy outcomes. An immunological cascade was suggested to be...
Eligibility Criteria
Inclusion
- Women 18 - 45 y.o.
- A score higher then 45 on the Zung Self-Rating Anxiety Scale or a score higher then 16 on the Center for Epidemiologic Studies Depression Scale
- Understanding of Hebrew
- Willing to sign the informed consent
Exclusion
- An axis I DSM IVTR diagnosis other then a depressive, adjustment or anxiety disorder
- Suicidal ideation
- Current treatment with antidepressant medication
- Physical illness explaining depressive symptoms (e.g. hypothyroidism, neurological disease, severe anemia, renal failure etc.)
- Alcoholism or drug abuse and dependence
- Past severe side effects to SSRIs
- Failed IVF (4 trials of good quality embryo reinstatement without achieving pregnancy)
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2012
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00989053
Start Date
January 1 2010
End Date
January 1 2012
Last Update
October 2 2009
Active Locations (1)
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1
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel