Status:
COMPLETED
Alcohol Exposure and Airway Hyperresponsiveness
Lead Sponsor:
University of Nebraska
Collaborating Sponsors:
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions:
Healthy
Eligibility:
MALE
21-65 years
Phase:
NA
Brief Summary
Alcohol has consequences including increased risk for upper respiratory tract infections, pneumonia, acute respiratory distress syndrome (ARDS), and alcohol-induced asthma. The investigators have esta...
Detailed Description
Alcohol has well-established consequences in the lung including increased risk for upper respiratory tract infections, pneumonia and acute respiratory distress syndrome (ARDS). There have even been a ...
Eligibility Criteria
Inclusion
- male
- must be of legal drinking age in the state of Nebraska (≥ 21)
- be between the ages of 21-65
- be non-smokers
- be able to dedicate 3-4 hours on two consecutive days (including waiting at least 2 hours after the alcohol ingestion)
- able to provide informed consent
Exclusion
- female
- inability to give informed consent
- any history of lung or allergic disease
- any alcohol intake for the week prior to the experiment
- self-identified history of chronic heavy drinking or alcoholism or psychiatric disorder
- If an otherwise qualifying participant has previously undocumented or unidentified asthma as indicated by the baseline methacholine challenge, that subject will be excluded from the remainder of the study and replaced by another subject
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 16 2013
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT00990275
Start Date
October 1 2009
End Date
January 16 2013
Last Update
September 6 2023
Active Locations (1)
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1
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198