Status:
COMPLETED
Association Between Laser Interferometric Measurement of Fundus Pulsation and Pneumotonometric Measurement of Pulsatile Ocular Blood Flow in Patients With Age-related Macular Degeneration
Lead Sponsor:
Medical University of Vienna
Conditions:
Age-related Macular Degeneration
Eligibility:
All Genders
50-90 years
Phase:
NA
Brief Summary
Several methods have been proposed for the measurement of pulsatile ocular blood flow (POBF). The pneumatic tonometer, which is commercially available, assesses POBF by measurement of intraocular pres...
Eligibility Criteria
Inclusion
- Patients with AMD (defined as soft drusen \> 63 µm, hyperpigmentation and/or hypopigmentation of the retinal pigment epithelium (RPE), RPE and associated neurosensory detachment, (peri)retinal hemorrhages, geographic atrophy of the RPE, or (peri)retinal fibrous scarring)
- Age between 50 and 90 years
Exclusion
- Evidence of any other retinal or choroidal vascular disease
- Regular use of pentoxifylline in the last month before the trial period
- Evidence of a choroidal neovascular membrane
- Diabetes mellitus
Key Trial Info
Start Date :
July 1 2001
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00991666
Start Date
July 1 2001
End Date
March 1 2011
Last Update
November 14 2014
Active Locations (1)
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1
Department of Clinical Pharmacology, Medical University of Vienna
Vienna, Austria