Status:
COMPLETED
Effects of the Atkins Diet Versus a Low Fat Diet on Inflammation
Lead Sponsor:
Boston Medical Center
Collaborating Sponsors:
Robert C. Atkins Foundation
Conditions:
Cardiovascular Health
Obesity
Eligibility:
All Genders
18-65 years
Phase:
PHASE3
Brief Summary
The purpose of this research is to assess the effects of a low-carbohydrate (modified Atkins) diet versus a low fat (Heart Healthy) diet on cardiovascular health.
Detailed Description
The purpose of this study is to compare the effects of a modified Atkins diet (low carbohydrate and low calorie) and a traditional heart healthy diet (low fat and low calorie) on biochemical markers o...
Eligibility Criteria
Inclusion
- Age 18-65 years
- BMI greater than or equal to 30
Exclusion
- Currently pregnant or lactating
- Type 2 diabetes
- Use of oral anti-diabetes medications (with exception of Metformin for control of PCOS)
- Presence of known peripheral arterial or cardiovascular disease
- Change in body weight (greater or equal to 3% within the past 3 months)
- Recent use (within the four weeks prior to screening) of weight loss medications including but not limited to phentermine, sibutramine, orlistat, or over the counter weight loss products
- History of an eating disorder or significant disordered eating behaviors such as binging/purging, abuse of laxatives or diuretics
- History of established renal or hepatic disease
- History of prior bariatric surgery
- Subjects who report routine tobacco use
- Subjects on Angiotensin receptor blockers (medications such as but not limited too Adicant, Losartan, Avapro, Diovan, Micardis, Teveten, Candesarten/thiazide, Ibesarten/thiazide, Valsartan/thiazide, Losarten/thiazide, Telmisarten/thiazide, Teveten/thiazide
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2011
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00993278
Start Date
August 1 2008
End Date
January 1 2011
Last Update
May 14 2015
Active Locations (1)
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1
Boston Medical Center
Boston, Massachusetts, United States, 02118