Status:

COMPLETED

Vitamin D to Improve Glucose Metabolism and Reduce Inflammation in Obese Adolescents

Lead Sponsor:

University of Missouri-Columbia

Conditions:

Obesity

Glucose Intolerance

Eligibility:

All Genders

9-19 years

Phase:

NA

Brief Summary

The investigators' project will study the effects of optimizing the vit D status of obese adolescents on markers of glucose metabolism and inflammation.

Detailed Description

The alarming rise in pediatric obesity over the past few decades has been associated with an increase in the occurrence of impaired glucose tolerance and inflammation in children and adolescents. Thes...

Eligibility Criteria

Inclusion

  • Obese adolescent (BMI \> 85th percentile for age)
  • 9-19 years of age
  • attending the ADOBE clinic at the University of Missouri

Exclusion

  • use of vit D supplements other than standard multi-vitamin preparation
  • (i.e., should not be receiving vit D \> 1000 IU/d) use of medications that interfere with vit D metabolism (e.g., anti-convulsive)
  • history of hepatic or renal disorders;
  • undergoing ultraviolet radiation as medical therapy;
  • pregnancy;
  • cigarette smoking;
  • current use of commercial tanning bed;

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2013

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT00994396

Start Date

November 1 2009

End Date

April 1 2013

Last Update

October 6 2016

Active Locations (1)

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1

University of Missouri

Columbia, Missouri, United States, 65211