Status:

COMPLETED

Tranexamic Acid in Pediatric Cardiac Surgery

Lead Sponsor:

Okayama University

Conditions:

Blood Loss

Congenital Heart Disease

Eligibility:

All Genders

2-18 years

Phase:

NA

Brief Summary

Tranexamic acid(TXA) is an antifibrinolytic agent to reduce blood loss in cardiac surgery. Previous seven RCTs comparing effects of TXA in pediatric cardiac surgery showed conflict results. The reason...

Eligibility Criteria

Inclusion

  • children undergoing elective cardiac surgery with cardiopulmonary bypass

Exclusion

  • neonate born within 1 month
  • preoperative inotropes
  • preoperative mechanical ventilation
  • preexisting coagulation disorder
  • reoperation within 48 hours
  • significant liver or kidney disease
  • known allergy to TXA

Key Trial Info

Start Date :

January 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2008

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT00994994

Start Date

January 1 2006

End Date

April 1 2008

Last Update

October 14 2009

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Tranexamic Acid in Pediatric Cardiac Surgery | DecenTrialz