Status:
COMPLETED
Following Lipectomy to Understand Adipose Tissue Re-accumulation
Lead Sponsor:
University of Colorado, Denver
Conditions:
Menopause
Pre-menopause
Eligibility:
FEMALE
35-60 years
Phase:
NA
Brief Summary
The typical female pattern of accumulating fat in the hips and thighs has long been thought to confer less risk for disease than the typical male abdominal fat pattern. However, leg fat may not simply...
Detailed Description
Lipectomy is the most frequently performed aesthetic surgery in the U.S. today and is considered permanent, by The American Society for Aesthetic Plastic Surgery, but no long term follow-up studies ha...
Eligibility Criteria
Inclusion
- post-menopausal (no menses for 12mo or oophorectomy w/ follicle-stimulating hormone (FSH)\>30 IU/L) OR- pre-menopausal (regular menses 28+/-3d)
- BMI \>20 and \<30 kg/m2)
- weight stable (+/- 2kg in past 2mo)
- non-smoking
- no use of hormone therapies or oral contraceptives
- actively seeking liposuction of the hips and thighs
- good femoral lipectomy candidates as determined by cosmetic surgeon
Exclusion
- severe hypertriglyceridemia (\>400 mg/dL)
- medications known to affect lipid metabolism
- elevated resting blood pressure (Systolic \>140 mm Hg,Diastolic \>90 mm Hg)
- history of lipectomy or gastric bypass surgery
- body dysmorphic disorder
- pregnant, lactating or intention of becoming pregnant
- indication of high surgical risk (e.g., abnormal resting ECG, history of thromboembolism, valvular heart disease)
Key Trial Info
Start Date :
January 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
53 Patients enrolled
Trial Details
Trial ID
NCT00995631
Start Date
January 1 2008
End Date
December 1 2014
Last Update
January 11 2017
Active Locations (1)
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1
University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States, 80045