Status:

COMPLETED

Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women

Lead Sponsor:

Sprout Pharmaceuticals, Inc

Conditions:

Sexual Dysfunctions, Psychological

Eligibility:

FEMALE

35+ years

Phase:

PHASE3

Brief Summary

The objective of this trial is to assess the safety and efficacy of 24-week course of flibanserin for the treatment of Hypoactive Sexual Desire Disorder (HSDD) in naturally postmenopausal women.

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Naturally postmenopausal women of any age with at least one ovary
  • Diagnosis of Hypoactive Sexual Desire Disorder, generalized acquired type,of at least six months duration
  • Stable, monogamous heterosexual relationship for at least one year
  • Willing to discuss sexual issues
  • Willing to engage in sexual activity at least once a month
  • Normal Pap smear
  • Normal mammogram
  • Normal uterine lining
  • Able to comply with daily use of handheld data entry device
  • Exclusion criteria:
  • Sexual dysfunctions other than HSDD, such as Sexual Aversion Disorder, Substance-induced Sexual Dysfunction, Dyspareunia, Vaginismus, Gender Identity Disorder, Paraphilia and Sexual Dysfunction due to a General Medical Condition
  • Partner with inadequately treated organic or psychosexual dysfunction
  • Sexual function impaired by psychiatric disorder
  • Sexual function impaired by gynecological disorder
  • Major Depression
  • Suicidal behavior or ideation
  • Major life stress that could impair sexual function
  • Substance abuse

Exclusion

    Key Trial Info

    Start Date :

    October 1 2009

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2011

    Estimated Enrollment :

    949 Patients enrolled

    Trial Details

    Trial ID

    NCT00996372

    Start Date

    October 1 2009

    End Date

    March 1 2011

    Last Update

    June 12 2014

    Active Locations (75)

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    Page 1 of 19 (75 locations)

    1

    511.130.01074 Boehringer Ingelheim Investigational Site

    Birmingham, Alabama, United States

    2

    511.130.01046 Boehringer Ingelheim Investigational Site

    Huntsville, Alabama, United States

    3

    511.130.01042 Boehringer Ingelheim Investigational Site

    Mobile, Alabama, United States

    4

    511.130.01025 Boehringer Ingelheim Investigational Site

    Phoenix, Arizona, United States