Status:
UNKNOWN
An Exploration of Genetic Testing for Prostate Cancer Susceptibility
Lead Sponsor:
Royal Marsden NHS Foundation Trust
Collaborating Sponsors:
Institute of Cancer Research, United Kingdom
Conditions:
Prostate Cancer
Eligibility:
MALE
40-69 years
Brief Summary
Study of the factors that affect interest in - and uptake of - genetic testing for variants that predispose to prostate cancer from the perspective of the patient.
Detailed Description
This study will use a mixed methods approach to follow men as they move through the genetic testing process, from initial contact through to receiving their genetic testing results. A questionnaire wi...
Eligibility Criteria
Inclusion
- Men with a positive family history of prostate cancer. The definition of a positive family history will be: Men with a first degree relative with prostate cancer diagnosed at \<70 years; Men with two relatives with prostate cancer where at least on is diagnosed at \<70 years; Men with three relatives with prostate cancer diagnosed at any age
- Age 40-69 years
- No previous biopsy for raised PSA
- Absence of any psychological, familial, sociological or geographic situation potentially hampering compliance with the study protocol and follow-up schedule.
Exclusion
- Previous prostate cancer
- Men from families where there is known to be a mutation in a high-risk prostate cancer gene
- Men who have had a prostate biopsy within the last 12 months.
Key Trial Info
Start Date :
August 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2011
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT00997464
Start Date
August 1 2009
End Date
February 1 2011
Last Update
October 19 2009
Active Locations (1)
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1
Royal Marsden NHS Foundation Trust
Sutton, Surrey, United Kingdom, SM2 5PT