Status:

COMPLETED

Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients

Lead Sponsor:

Hurley Medical Center

Conditions:

Inhalation Injury

Pneumonitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The investigators hypothesize that the scheduled use of bronchoscopy on a regular basis after inhalation injury in burn patients will improve outcome by providing pulmonary hygiene, decrease the incid...

Detailed Description

The role of bronchoscopy in most hospitals has been limited to obtaining lavage fluid for culture and assessing the degree of airway injury, which has been shown to be predictive of outcome. Severe in...

Eligibility Criteria

Inclusion

  • Any burned patient arriving intubated on mechanical ventilation OR requiring mechanical ventilation within 48 hours of admission AND
  • \> 18 years old AND
  • patient believed to be able to survive more than 48 hours after arrival (not likely to be made DNR or comfort care) including:
  • any methamphetamine explosion or
  • any burn associated with fire (not chemical) of the face or blast injury to the face or
  • confined in a burning space for more than 10 minutes or
  • any burn with carbonaceous material around the nose or mouth or
  • any burn \> 15% TBSA associated with fire (not chemical) or
  • any burn associated with an explosion in a confined space.

Exclusion

  • Likely to die within 48 hours based upon severity of injury.
  • Less than 18 years old.
  • Burned patient transferred to our facility already on mechanical ventilation for more than 48 hours.
  • Patient already on antibiotics for another reason.

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2012

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT00997555

Start Date

October 1 2009

End Date

July 1 2012

Last Update

January 31 2013

Active Locations (1)

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Hurley Medical Center

Flint, Michigan, United States, 48503