Status:
COMPLETED
Surveillance of Influenza Virus Shedding and Immunologic Response in Immunocompromised Children and Young Adults
Lead Sponsor:
St. Jude Children's Research Hospital
Conditions:
Influenza Virus
Eligibility:
All Genders
Up to 21 years
Brief Summary
Influenza virus infections are a major cause of morbidity and mortality. The limited existing knowledge about the impact of influenza in immunocompromised patients suggests that they are at increased ...
Detailed Description
This study aims to do the following; * To evaluate the frequency of influenza virus infections due to various subtypes in immunocompromised children and young adults at SJCRH * To describe and compar...
Eligibility Criteria
Inclusion
- Age \<= 21 years of age at the time of entry into the study.
- Body weight of 13 kg or greater
- An immunosuppressed state due to cancer, sickle cell disease, HIV, or receipt of stem cell transplant
- Presentation with acute respiratory illness defined as recent onset of rhinorrhea, nasal and sinus congestion, pharyngitis, coryza, sinusitis, otitis media, dyspnea or shortness of breath, cough and/or a new radiographic pulmonary infiltrates.
- Proven influenza virus infection by virological testing of respiratory specimens using Polymerase Chain reaction (PCR) assay, direct antigen detection assay, or viral culture.
Exclusion
- Inability or unwillingness of research participant or legal guardian to give written informed consent.
Key Trial Info
Start Date :
October 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT00998803
Start Date
October 1 2009
End Date
June 1 2012
Last Update
November 1 2012
Active Locations (1)
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1
St . Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105