Status:

COMPLETED

Dexmedetomidine Versus Propofol in Vitreoretinal Surgery

Lead Sponsor:

Rutgers, The State University of New Jersey

Conditions:

Retinal Detachment

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

The investigators would like to determine if using Dexmedetomidine alone or in a reduced dose can prevent or reduce the incidence of adverse effects, while providing adequate sedation, and respiratory...

Detailed Description

Alpha2 adrenergic receptor agonist have been used increasingly as a new armamentarium to provide sedative/hypnotic, analgesic, anxiolytic and sympatholytic effects in the perioperative settings. Dexme...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiologists rating of I-III
  • good renal and liver function

Exclusion

  • renal and hepatic insufficiency
  • uncontrolled diabetes
  • uncontrolled hypertension
  • severe cardiac disease Class III or IV
  • heart blocks
  • chronic use of sedatives, narcotics, alcohol or illicit drugs
  • allergy to either propofol or dexmedetomidine
  • pregnancy or inability to tolerate technique of the study drugs

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2013

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT01001429

Start Date

October 1 2009

End Date

November 1 2013

Last Update

August 21 2017

Active Locations (2)

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Page 1 of 1 (2 locations)

1

UMDNJ-University Hospital

Newark, New Jersey, United States, 07102

2

University Hospital

Newark, New Jersey, United States, 07102