Status:

COMPLETED

Comparative Effects of Milk Thistle Extract With Vitamin-E in Hemodialysis Patients

Lead Sponsor:

Shiraz University of Medical Sciences

Conditions:

Hemodialysis

End Stage Renal Disease

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

Brief Summary

For end-stage renal disease (ESRD) patients, cardiovascular disease remains the single most common cause of excess morbidity and mortality. Among the examined nontraditional risk factors, an increase ...

Eligibility Criteria

Inclusion

  • All hemodialysis patients age 18-60
  • On hemodialysis for over 3 months, 3 times a week, and for 4 hours each time
  • Signed informed consent

Exclusion

  • Heart Failure NYHA Class III or IV
  • Recent MI (within 1 year)
  • Use of anti-oxidant supplements: N-acetyl-cystein, Omega 3, Vit C, Vit E, green tea, soy extracts, pomegranate extract, grape extract..
  • Hepatitis B or C
  • Active Infection
  • Psychiatric illness
  • Active malignancy

Key Trial Info

Start Date :

June 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2010

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT01001845

Start Date

June 1 2009

End Date

May 1 2010

Last Update

January 24 2011

Active Locations (1)

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1

Nemazi Hospital

Shiraz, Fars, Iran, 71345