Status:

WITHDRAWN

The Effect of Weight Loss on Psoriasis Area Severity Index in Adult Psoriasis Patients

Lead Sponsor:

The University of Texas Health Science Center, Houston

Collaborating Sponsors:

National Institutes of Health (NIH)

Conditions:

Psoriasis

Obesity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effect that weight loss has on the severity of psoriasis in obese subjects. Fifty obese (BMI equal to or greater than 30) patients with moderate to severe ...

Eligibility Criteria

Inclusion

  • \>18 years of age
  • A Body Mass Index (BMI) \>/= 30
  • Subject has plaque psoriasis
  • A Psoriasis Area Severity Index (PASI) score \>/= 10 or a total body surface area (BSA) affected by psoriasis \>/= 10%
  • Capable of reading, understanding, and signing a consent form
  • Females of childbearing potential must have negative urine pregnancy test on Day 0, and agree to a medically effective method of birth control (as determined by the investigator)

Exclusion

  • Already participating in a study for weight loss or a study of other psoriasis treatments
  • If they are on systemic therapy for their psoriasis
  • Female subjects who are pregnant or planning to become pregnant
  • Patients with a history of anorexia nervosa, bulimia, or other diseases that would make a weight loss program a risk to their health
  • Subjects unable to comply with study protocol

Key Trial Info

Start Date :

June 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2013

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01137448

Start Date

June 1 2010

End Date

May 1 2013

Last Update

December 16 2013

Active Locations (1)

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University of Texas Dermatology Clinical Research

Houston, Texas, United States, 77030