Status:

COMPLETED

Biomarkers in Patients With Acute Myeloid Leukemia

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

Brief Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This r...

Detailed Description

OBJECTIVES: * To determine whether clonally expanded somatic mitochondrial DNA mutations are associated with acute myeloid leukemia. OUTLINE: Genomic DNA from blood samples obtained at diagnosis, re...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of acute myeloid leukemia
  • Available blood samples from diagnosis, remission, and relapse
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    February 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    Estimated Enrollment :

    18 Patients enrolled

    Trial Details

    Trial ID

    NCT01138319

    Start Date

    February 1 2009

    Last Update

    May 6 2015

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