Status:
COMPLETED
The Protective Effect of Ginkgo Biloba Extract on Cisplatin-induced Ototoxicity in Humans
Lead Sponsor:
University of Brasilia
Conditions:
Ototoxicity
Hearing Loss
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The proposal of this study was to evaluate in human beings, using distortion product otoacoustic emission (DPOAE) test, the action of ginkgo biloba extract (GBE761)as a possible ear protective against...
Detailed Description
The ototoxicity is an alteration caused by drugs that compromises the auditory and vestibular functions. The cisplatin (CDDP) is a potent antineoplastic agent used for the treatment of cancer in both ...
Eligibility Criteria
Inclusion
- Over the age of eighteen
- Patients that will begin treatment with cisplatin
- No prior treatment with cisplatin
Exclusion
- Individuals with middle ear, cochlear or retrocochlear disease
- Presence of changes in pure tone audiometry and/or distortion-product otoacoustic emissions
Key Trial Info
Start Date :
June 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2008
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT01139281
Start Date
June 1 2007
End Date
June 1 2008
Last Update
June 8 2010
Active Locations (1)
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1
Hospital de Base do Distrito Federal (HBDF)
Brasília, Federal District, Brazil, 70000-000