Status:

COMPLETED

Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

Multiple Myeloma

Leukemia

Eligibility:

MALE

18-100 years

Brief Summary

Background: \- Multiple myeloma (MM), a type of cancer that affects the white blood cells, is often preceded by a precancerous disorder known as monoclonal gammopathy of undetermined significance (MG...

Detailed Description

We propose to conduct a molecular epidemiology study with a subset of participants in the Agricultural Health Study (AHS), a prospective cohort of 57,310 licensed pesticide applicators in Iowa and Nor...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Selected participants in the Agricultural Health Study are invited to participate in this aspect of the study.
  • Male private pesticide applicator;
  • Alive as of the latest update of the National Death Index G\\fDD and over 50 years of age at the time of initial contact:
  • Cancer free as of the most recent linkage with the appropriateCancer Registry;
  • Completed phase I, II and III interviews (these study subjects have the most comprehensive exposure evaluation and also will be the most interested in the study).
  • EXCLUSION CRITERIA:
  • Deceased or no longer residing in Iowa or North Carolina;
  • Ever diagnosed with any type of cancer other than non-melanoma skin cancer;
  • Unable to speak English;
  • Have a blood clotting disorder such as hemophilia; or
  • Registered with the AHS as a "no contact".

Exclusion

    Key Trial Info

    Start Date :

    June 15 2010

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    Estimated Enrollment :

    1892 Patients enrolled

    Trial Details

    Trial ID

    NCT01139476

    Start Date

    June 15 2010

    Last Update

    January 8 2026

    Active Locations (1)

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    1

    University of Iowa

    Iowa City, Iowa, United States, 52242