Status:
COMPLETED
Manipulation of Visceral Hypersensitivity With Probiotic Bacteria in Irritable Bowel Syndrome
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Irritable Bowel Syndrome
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
Irritable bowel syndrome is a common digestive disorder worldwide. However, there is no effective treatment of irritable bowel syndrome. Visceral pain thresholds in response to stress are lower in pat...
Detailed Description
Background An incomplete understanding of the mechanisms underlying irritable bowel syndrome (IBS) has hampered the development of an effective therapy for this condition. This is long overdue for a ...
Eligibility Criteria
Inclusion
- Symptoms of abdominal pain or discomfort of at least 3 times a month, in the last 6 months, associated with 2 or more of the following:
- Improvement with defecation
- Onset associated with a change in frequency of stool
- Onset associated with a change in form (appearance) of stool
Exclusion
- history of weight loss or rectal bleeding
- history of psychiatric illness (severe depression, mania and schizophrenia)
- history of active infection
- recent antibiotic therapy or anti-inflammatory medication
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2011
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT01139736
Start Date
July 1 2010
End Date
March 1 2011
Last Update
January 21 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Prince of Wales Hospital
Shatin, Hong Kong