Status:
COMPLETED
Association Between Framingham Risk Score, hsCRP and Vascular Inflammation: Analysis With 18F-Fluorodeoxyglucose Positron Emission Tomography
Lead Sponsor:
Korea University Guro Hospital
Conditions:
Cardiovascular Risk
Eligibility:
All Genders
16-80 years
Brief Summary
Framingham risk score is well known screening tool that detect cardiovascular (CV) risk. But it is not suitable for CV risk in mild risk group. So 18F-fluorodeoxyglucose positron emission tomography (...
Detailed Description
We examined vascular inflammation using FDG-PET scan in 178 subjects (Normal and impaired glucose tolerance groups). Vascular 18F-FDG uptake was measured as both the mean and maximum blood-normalized ...
Eligibility Criteria
Inclusion
- healthy subjects
Exclusion
- a history of cardiovascular disease (myocardial infarction, unstable angina, stroke or cardiovascular revascularization)
- active inflammatory disease, recent active infection
- stage 2 hypertension (resting blood pressure, ≥ 160/100 mmHg)
- diabetes mellitus
- systemic disorders such as severe hepatic, renal, and hematologic diseases
- taking drugs known to interfere with vascular inflammation measured by FDG-PET.
Key Trial Info
Start Date :
September 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
178 Patients enrolled
Trial Details
Trial ID
NCT01139827
Start Date
September 1 2009
End Date
February 1 2010
Last Update
June 9 2010
Active Locations (1)
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1
Korea university guro hospital
Seoul, South Korea