Status:
COMPLETED
Biomarkers in Tissue and Blood Samples From Patients With Early-Stage Non-Small Cell Lung Cancer
Lead Sponsor:
Alliance for Clinical Trials in Oncology
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
RATIONALE: Studying samples of blood and tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer....
Detailed Description
OBJECTIVES: * Evaluate aberrant methylation patterns in tissue and serum samples from patients with early-stage non-small cell lung cancer (NSCLC) to validate the Johns Hopkins single institutional s...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of early-stage non-small cell lung cancer
- T1 or T2, N0 disease
- Had a lobectomy or greater resection with negative surgical margins (R0 resection)
- Available tumor and lymph node specimens from patients enrolled on ACOSOG-Z0040 and ACOSOG-Z0030 trials
- Node-negative with recurrent disease within 3 years (cases)
- Node-negative patients without recurrent disease (controls)
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Exclusion
Key Trial Info
Start Date :
July 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT01139944
Start Date
July 1 2010
End Date
January 1 2014
Last Update
July 6 2016
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