Status:

COMPLETED

Face Transplantation

Lead Sponsor:

University of Maryland, Baltimore

Conditions:

Transplantation: Facial Transplantation

Eligibility:

All Genders

18-64 years

Phase:

NA

Brief Summary

This study aims to: 1. Perform face transplants on people who have suffered severe facial trauma with tissue and functional loss; and 2. Evaluate the acceptance and function of the transplanted tissu...

Detailed Description

For patients with severe facial deformities or facial wounds from traumatic injuries, we would like to pursue the use of a face transplant to help reconstruct a person's damaged face. Our goal is to n...

Eligibility Criteria

Inclusion

  • 18-64 years of age
  • Facial defect or injury requiring facial transplantation as determined by the treating Plastic and Reconstructive Surgeon
  • Signed written informed consent
  • Able to complete psychiatric evaluations
  • Willing and able to continue immunosuppression regimen as directed by treating physician
  • Willing and able to return for follow-up visits as described in the treatment plan
  • Must have autogenous tissue options available for reconstruction in event of graft failure
  • Laboratory values as defined by research protocol
  • Willing to undergo review by Participant Selection Committee and be placed on a transplant recipient waitlist

Exclusion

  • Pre-existing disease that would exclude the recipient from transplantation
  • Active infection
  • Ongoing substance abuse
  • HIV positive
  • Positive for Hepatitis B or C
  • Active malignancy
  • Pregnant or breastfeeding

Key Trial Info

Start Date :

September 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 14 2020

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT01140087

Start Date

September 1 2010

End Date

August 14 2020

Last Update

September 30 2021

Active Locations (1)

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1

University of Maryland, Baltimore

Baltimore, Maryland, United States, 21201