Status:

COMPLETED

The Electroretinogram in Healthy and Glucose Intolerant Young Men

Lead Sponsor:

Glostrup University Hospital, Copenhagen

Conditions:

Electroretinography

Eligibility:

MALE

18-35 years

Phase:

NA

Brief Summary

The purpose is to investigate the electroretinogram (ERG) in young, healthy men in the normoglycaemic and hyperglycaemic state before and after intervention with corticosteroids treatment, high calori...

Detailed Description

The subjects will be fasting from midnight the day before the experiment. Standard procedures (including pupil dilation, dark adaptation, and local anaesthetics) are carried out to allow the ERG to be...

Eligibility Criteria

Inclusion

  • Caucasians without type 2 diabetes mellitus
  • Normal OGTT (75 g glucose dissolved in 250 mL water) according to WHO's criteria
  • BMI 20-30
  • Haemoglobin \> 8,0 mM

Exclusion

  • Nephropathy (s-creatinin \> 130 µM or albuminuria)
  • Relatives (parents or sibling with T2DM)
  • Medical treatment which cannot be paused for 12 hours

Key Trial Info

Start Date :

February 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01140932

Start Date

February 1 2010

End Date

June 1 2010

Last Update

December 8 2010

Active Locations (1)

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1

Copenhagen University Hospital at Glostrup

Copenhagen, Copenhagen, Denmark, DK-2600