Status:
COMPLETED
Effects of Bronchodilation on Computed Tomography (CT) Parameters Reflecting Airways Remodelling, and Pulmonary Emphysema Extent.
Lead Sponsor:
Erasme University Hospital
Collaborating Sponsors:
Centre Hospitalier Universitaire Saint Pierre
Conditions:
COPD
CT
Eligibility:
All Genders
18+ years
Brief Summary
CT studies considering bronchial dimensions in chronic obstructive pulmonary disease (COPD) were conducted without control of bronchodilation. Some data however suggest that total lung capacity (CT sc...
Detailed Description
Patients : COPD patients aged 40 years or more, with a smoking history of \> 10 pack-years (PY) and a post-bronchodilator forced expiratory volume in one second to vital capacity ratio (FEV1/VC) \< 0....
Eligibility Criteria
Inclusion
- age 40 or more
- Smoking history \> 10 pack-years
- post bronchodilator FEV1/VC \< 0.7
Exclusion
- COPD exacerbation or infection in the 4 weeks before the study
- Concomitant pulmonary disease (tuberculosis, significant bronchiectasis, lung cancer)
- pulmonary resection
- active malignancy or malignancy of any organ system within the past 5 years
Key Trial Info
Start Date :
March 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01142531
Start Date
March 1 2010
End Date
June 1 2011
Last Update
July 4 2012
Active Locations (1)
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1
C.H.U Saint-Pierre
Brussels, Belgium, 1000