Status:
COMPLETED
Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis
Lead Sponsor:
Federal University of Minas Gerais
Collaborating Sponsors:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Fundação de Amparo à Pesquisa do estado de Minas Gerais
Conditions:
Dental Plaque
Gingivitis
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
Brief Summary
Mouthwash based on medicinal plants and propolis can be easily found in the Brazilian market even if it has not been tested in reliable clinical trials on its efficacy or possible unpleasant side effe...
Detailed Description
The first reference to mouthrinse as a formal practice is credited to Chinese medicine, about 2700 B.C.E., to treatment the diseases of the gums (Fischman, 1997). The gram-positive and gram-negative ...
Eligibility Criteria
Inclusion
- age 18-60 years
- generally good health
- not pregnant nor breastfeeding
- a minimum of 20 sound, natural teeth
- a mean plaque index (PI) (Turesky modification of the Quigley-Hein Plaque Index, 1970) of at least 1.5 or more
- a mean gingival index (GI) (Talbott modification Gingival Index of the Löe-Silness, 1977) of at least 1.0 or more
- signing the terms of agreement
Exclusion
- Subjects with orthodontic appliances or removable prosthetics
- Subjects with tumors of the soft or hard oral tissues
- Subjects with advanced periodontal disease
- Subjects that received antibiotic therapy 2 weeks before the start of the study
- Subjects with hipersensibility to propolis confirmed
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2010
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT01142843
Start Date
August 1 2009
End Date
March 1 2010
Last Update
July 2 2010
Active Locations (1)
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1
Universidade Federal de Minas Gerais (UFMG)
Belo Horizonte, Minas Gerais, Brazil, 31270-901