Status:
RECRUITING
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Metabolic Disease
Obesity
Eligibility:
All Genders
1-100 years
Brief Summary
Background: \- Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseas...
Detailed Description
We propose to characterize the etiology and natural history of rare and uncommon diseases, both known and unknown that present with symptoms and signs associated with the risk of overt or potential ca...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Eligible subjects may include anyone over 1 year of age who is affected with diseases/disorders (index cases), or who is a relative of a person who is affected with diseases/disorders. Relatives may include genetic carriers and non-carriers.
- Healthy adult volunteers must be 18 years of age or older, and must agree to have blood or tissue samples studied, and potentially stored for future research.
- Index cases enrolled in this protocol will have been referred with a known or suspected pathology that may be associated with cardiovascular dysfunction or risk with a suspected atypical presentation, heritable disorder, or genetic predisposition. The investigator with expertise in the presentation of the subject, along with consulting specialists, will review the medical history and may review any medical records that are available of prospective subjects and offer admission based upon the potential to help the individual, to learn from the subject, or to initiate clinical or basic research suggested by the subject s workup.
- EXCLUSION CRITERIA:
- Persons of less than 1 year of age or greater than 100 years of age
- Healthy volunteers unable to give informed consent or who decline to have blood and/or tissue studies, or who do not consent to have samples stored for future research may be excluded from this study.
- Pregnant women
- Persons who are not fluent in the English language will be excluded from Patient Reported Outcome Questionnaires. Such persons would be unable to properly complete questionnaires that are only valid in the English language.
Exclusion
Key Trial Info
Start Date :
July 21 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT01143454
Start Date
July 21 2010
Last Update
December 31 2025
Active Locations (2)
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1
Suburban Hospital
Bethesda, Maryland, United States, 20814
2
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892