Status:
COMPLETED
Glutamate and Diastolic Function in Patients Undergoing Aortic Valve Repair
Lead Sponsor:
Medical University of Vienna
Conditions:
Hypertrophy, Left Ventricular
Aortic Stenosis
Eligibility:
All Genders
19-90 years
Phase:
PHASE4
Brief Summary
Purpose: The effect of intravenous glutamate infusion on myocardial diastolic function and overall hemodynamics were studied in patients undergoing elective aortic valve replacement with severe aortic...
Eligibility Criteria
Inclusion
- severe aortic stenosis
- left ventricular hypertrophy of more than 10mm IVS thickness
- normal ejection fraction
- SR
Exclusion
- moderately or severely reduced systolic left ventricular function (ejection fraction \<30%)
- atrial fibrillation or flutter
- intolerance to glutamate.
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2008
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT01144039
Start Date
February 1 2006
End Date
September 1 2008
Last Update
June 16 2010
Active Locations (1)
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1
Clin. Dept. of Cardiothoracic and Vascular Anaesthesia & Intensive Medicine, Medical University of Vienna, Vienna General Hospital
Vienna, Vienna, Austria, 1090