Status:

COMPLETED

Exercise Intensity, Glycemic Control and Abdominal Fat in People With Type 2 Diabetes: A Pilot Study

Lead Sponsor:

University of Alberta

Collaborating Sponsors:

Alberta Diabetes Institute

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

55-75 years

Phase:

NA

Brief Summary

Body fat is an important risk factors for type 2 diabetes. However, not all body fat is the same. Research suggests that fat stored in the abdomen is most harmful. This is known as intra-abdominal fat...

Eligibility Criteria

Inclusion

  • Men and women with type 2 diabetes.
  • From 55-75 years of age (Women post-menopausal for at least 5 years).
  • Sedentary: \< 3 bouts of planed physical activity of \>30 min per week.

Exclusion

  • Smoking (defined as more than one cigarette per day).
  • Inability to speak and read English.
  • Diseases known to affect body fat distribution (e.g., polycystic ovary syndrome, Cushing's syndrome, HIV-AIDS or lipodystrophies).
  • Taking medications that may affect body fat distribution (e.g., Thiazolidinedione, Insulin, Growth Hormone).
  • Limitations to regular exercise training (e.g., musculoskeletal limitations, heart disease, chronic obstructive pulmonary disease).
  • Answering "yes" to any of the questions on the physical activity readiness questionnaire (PAR-Q).
  • Having undergone major changes in physical activity, diet or medication in the previous 6 months (or be planning such changes in the next 4 months). Changes in physical activity will be considered as an increase or decrease of more than 1 hour per week. A change in body weight greater 3 kg will also lead to exclusion.
  • Body weight \> 300 lbs (maximum weight for Dual Energy X-Ray Absorptiometry (DXA) table).
  • HbA1c \> 0.09%
  • blood pressure above 140/90 mmHg.
  • LDL cholesterol above 3.5 mmol/L or TC:HDL-C above 5.0.
  • Self-reported alcohol or substance abuse within the past twelve months, current consumption of more than 14 alcoholic drinks per week, and/or current acute treatment or rehabilitation program for these problems.
  • Other medical or psychiatric factors that in the judgment of the principal investigators may interfere with study participation or the ability to follow the study protocol.

Key Trial Info

Start Date :

June 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT01144078

Start Date

June 1 2010

End Date

June 1 2011

Last Update

January 5 2012

Active Locations (1)

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1

University of Alberta

Edmonton, Alberta, Canada, T6G 2H9