Status:

COMPLETED

A Prospective, Noninterventional Follow-Up Study of Children Aged 23 to 25 Months, Born to Mothers Who Received Hydroxyprogesterone Caproate Injection, 250 mg/mL, or Vehicle for Prevention of Preterm Birth

Lead Sponsor:

AMAG Pharmaceuticals, Inc.

Collaborating Sponsors:

Registrat-Mapi

Conditions:

Children Whose Mothers Received 17P and Those Who Received Vehicle in the 17P Efficacy Trial

Eligibility:

All Genders

22-25 years

Brief Summary

In the continuing efforts to understand the benefits and risks of in utero exposure to 17P this study is designed to evaluate differences in developmental outcomes of children, aged 23 to 25 months, b...

Detailed Description

This will be a prospective, noninterventional follow-up study designed to provide a developmental assessment of children born to mothers who participated in the 17P Efficacy Trial. When subjects reach...

Eligibility Criteria

Inclusion

  • 1\. Maternal enrollment which resulted in a live birth in the 17P Efficacy Trial: A Multi-center, Randomized, Double-blind Study of Hydroxyprogesterone Caproate Injection, 250 mg/mL, Versus Vehicle for the Prevention of Preterm Birth in Women With a Previous Singleton Spontaneous Preterm Delivery.
  • 2\. During their involvement in the above protocol, mothers must have received at least one dose of study drug (Safety population).
  • 3\. Children between 22 and 25 months of age adjusted for gestational age.

Exclusion

  • 1\. There is no parent/legal guardian available to sign an informed consent. 2. Born to women who are unblinded to study group assignment.

Key Trial Info

Start Date :

November 9 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 13 2020

Estimated Enrollment :

245 Patients enrolled

Trial Details

Trial ID

NCT01146990

Start Date

November 9 2010

End Date

August 13 2020

Last Update

May 18 2022

Active Locations (40)

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Page 1 of 10 (40 locations)

1

Drug Research Analysis Corp

Montgomery, Alabama, United States, 36106

2

Watching Over Mothers and Babies Foundation

Tucson, Arizona, United States, 85712

3

Grossmont Center for Clinical Research

La Mesa, California, United States, 91942

4

Naval Medical Center San Diego

San Diego, California, United States, 92124