Status:
COMPLETED
The Effect of Magnesium Sulfate on Motor and Somatosensory Evoked Potentials in Children Undergoing Scoliosis Surgery
Lead Sponsor:
The Hospital for Sick Children
Conditions:
Scoliosis
Eligibility:
All Genders
12-18 years
Phase:
PHASE2
Brief Summary
The primary objective of this study is to determine whether magnesium sulfate has a clinically important effect on the amplitude and latency of somatosensory and motor evoked potentials in patients un...
Detailed Description
Motor and somatosensory evoked potentials are continuously monitored in the setting of scoliosis surgery to evaluate the integrity of spinal cord pathways. Detection of neural irritation or injury usi...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists (ASA) status I or II
- Adolescent children aged 12 to 18 years undergoing surgery for idiopathic scoliosis
Exclusion
- Magnesium use within the last two weeks, either intravenous or oral supplements
- Patients with known electrolyte imbalances or conduction disorders. (Sodium \<135 or \>143 mmol/L OR Potassium \< 3.7 or \> 5.0 mmol/L if 12 to 15 yrs; Potassium \<3.7 or \>4.8 mmol/L if 16 to 18 yrs)
- Renal, cardiac or neuromuscular disorders.(Urea \< 2.9 or \> 7.1 mmol/L OR Creatinine \>79 µmol/L if \< 13 yrs; Creatinine \> 98 µmol/L if \>= 14 yrs)
Key Trial Info
Start Date :
June 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT01148888
Start Date
June 1 2010
End Date
December 1 2012
Last Update
November 19 2014
Active Locations (1)
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1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8