Status:

COMPLETED

Immune Response to Influenza Vaccine in Islet Cell Transplant Recipients

Lead Sponsor:

University of Alberta

Conditions:

Transplant

Eligibility:

All Genders

18-75 years

Brief Summary

Influenza virus is an important cause of morbidity in the transplant population and can lead to viral and bacterial pneumonia. Although the annual influenza vaccine is recommended for organ transplant...

Detailed Description

OBJECTIVE AND HYPOTHESIS * To test the specific humoral response of the influenza vaccine after islet cell transplantation * To test the production of HLA alloantibodies after vaccination.

Eligibility Criteria

Inclusion

  • Adult islet cell transplant recipients
  • Able to provide informed consent

Exclusion

  • Egg allergy
  • Previous life-threatening reaction to influenza vaccine (ie Guillain Barre Syndrome)
  • Febrile illness in the past two weeks
  • Unable to provide informed consent

Key Trial Info

Start Date :

August 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2011

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT01149382

Start Date

August 1 2010

End Date

December 1 2011

Last Update

August 21 2012

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Alberta Hospital

Edmonton, Alberta, Canada, T6G 2E1