Status:
COMPLETED
Effect of a Probiotic on Grass Pollen Allergic Rhinitis Subjects
Lead Sponsor:
Société des Produits Nestlé (SPN)
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
Various studies in animals and humans have shown a potential beneficial effect of probiotics consumption on allergy. However, few studies exist that document their efficacy for upper airways allergies...
Eligibility Criteria
Inclusion
- age 18 to 35 years
- history of allergic rhinitis to grass pollen confirmed by either a positive skin prick test (wheal diameter \>3 mm) or specific IgE for grass pollen (\>0.35 kU/L) as titrated by UniCAP 100 (Pharmacia Diagnostics, Uppsala, Sweden) and no history of perennial rhinitis
- a nasal reaction threshold of 10'000 standardized quality units (SQs)/ml grass pollen or less at the screening phase
Exclusion
- any medical condition that could influence the study (pregnancy, viral or bacterial airway infection, active allergic rhinitis)
- uncontrolled asthma (peak expiratory flow \<20% of volunteer's best personal value)
- treatment with antihistamine or antibiotic treatment less than two weeks before enrolment or during the trial
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
End Date :
March 1 2007
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01150253
Start Date
August 1 2006
End Date
March 1 2007
Last Update
January 14 2014
Active Locations (1)
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1
Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland, 1011