Status:
COMPLETED
Epidemiology of Non-syndromic Dominant Deafness
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Hearing Impairment
Eligibility:
All Genders
4+ years
Brief Summary
Hearing impairment is a common disorder that affects at least 7% of individuals in our countries. Even the causes of hearing impairment are numerous, genetic causes represent the main factor of sensor...
Detailed Description
The protocol consists first in the recruitment of 150 families with non syndromic dominant hearing impairment. The families will be recruited by the clinical investigators. The clinic and radiological...
Eligibility Criteria
Inclusion
- Age \> 4 years.
- Patient presenting familial dominant non syndromic hearing loss starting between 4 and 40 years old, over 2 generations
- Healthy volunteer from the same families
- Clinical and paraclinical assessment (genetic and ophthalmologic examination, audiometric tests, inner ear CT scan)
- Affiliated to the national health insurance benefit
- Signature of informed consent form
Exclusion
- hearing loss resulting from an extrinsic reason or an associated syndrome
- Defective or insufficient samples
- No or insufficient clinical and biological description
- No informed consent form
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2012
Estimated Enrollment :
183 Patients enrolled
Trial Details
Trial ID
NCT01150305
Start Date
April 1 2009
End Date
April 1 2012
Last Update
August 7 2013
Active Locations (1)
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1
Hôpital Armand-Trousseau, Service d'ORL pédiatrique et de Chirurgie Maxillo Faciale
Paris, France, 75012