Status:
COMPLETED
Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial
Lead Sponsor:
Università degli Studi dell'Insubria
Conditions:
Acute Lung Injury
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The main hypothesis are: 1. Passive and Active-Passive airway conditioning devices reduce the incidence of ventilator associated pneumonia 2. Active-Passive airway conditioning devices reduce the inc...
Detailed Description
For all Three lines of the study we record Clinical Pulmonary Infection score and Airways Care Score, SOFA (Sequential Organ Failure Assessment), sedation strategy, Glasgow Coma Score and clinical dat...
Eligibility Criteria
Inclusion
- Patients mechanically ventilated with PaO2/FiO2 lower than 300
- Age higher than 18 years
- Invasive mechanical ventilation
- Endotracheal intubation or tracheostomy for more than 24 hours
Exclusion
- Non invasive ventilation
- Severe ARDS (PaO2/FiO2 lower than 100, or PaCO2 higher than 60 mmHg)
- Inefficient cough
- Head Trauma
- Spinal cervical trauma
- Chest trauma
- Pregnancy
- Expectance of poor survival within 72 hours
- Congenital airway disease
- Immunosuppression
- Supraglottic aspiration devices
Key Trial Info
Start Date :
April 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2017
Estimated Enrollment :
190 Patients enrolled
Trial Details
Trial ID
NCT01150864
Start Date
April 1 2010
End Date
March 1 2017
Last Update
May 25 2017
Active Locations (1)
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1
Ospedale di Circolo
Varese, Italy, 21100