Status:
WITHDRAWN
Noninvasive Positive Pressure Ventilation for Early Extubation of Acute Hypoxemic Respiratory Failure
Lead Sponsor:
Beijing Chao Yang Hospital
Conditions:
Acute Hypoxemic Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Acute hypoxaemic respiratory failure (AHRF) refers to pathological states in which arterial blood oxygenation is severely impaired，and which need invasive positive pressure ventilation (IPPV) as respi...
Eligibility Criteria
Inclusion
- Orotracheal intubation
- Arterial oxygen tension (PaO2)\<60mmHg（venturi mask，FiO2=0.5），and arterial carbon dioxide tension(PaCO2)≤45mmHg；
- Meeting standard criteria for weaning readiness
- Suffering failure of spontaneous breathing trial.
Exclusion
- Age\<18
- Duration of invasive positive pressure ventilation\<48h
- Tracheotomy
- Percentage of cuff leak volume in tidal volume\<15.5%
- Unable to spontaneously clear secretions from their airway
- Recent oral，nasal，facial or cranial trauma or surgery
- Recent gastric or esophageal surgery
- Active upper gastro-intestinal bleeding
- Severe abdominal distension
- Lack of co-operation
- Chronic respiratory disease such as chronic obstructive pulmonary disease，asthma，interstitial lung disease,etc.
Key Trial Info
Start Date :
July 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01151501
Start Date
July 1 2010
End Date
June 1 2012
Last Update
May 22 2019
Active Locations (1)
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1
Beijing Chao Yang Hospital
Beijing, Beijing Municipality, China, 100020